Phagebiotics Research Foundation
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Our Mission
The Phagebiotics Research Foundation studies and promotes the medical and veterinary applications of bacteriophages in the treatment of bacterial infections and related disorders.
Our Principles
- We are focused on advancing bacteriophage therapy as a tool to address the growing threat of antibiotic resistance.
- We support projects that build the scientific knowledge and infrastructure needed to conduct physician-initiated, controlled clinical trials in the United States and in collaboration with international colleagues.
- As a nonprofit research foundation focused on science and community need, we are committed to making findings supported by our efforts publicly available to help advance the field.
Our Goals
- Support collaborative research that helps clarify the safety and efficacy of phage therapy for key clinical applications.
- Bring together medical and scientific communities across countries and disciplines to coordinate research efforts for the greatest possible impact.
- Collaborate with other interested parties working toward broader regulatory approval of phage-based therapeutics.
- Develop a forum for establishing evidence-based phage therapy clinical practice and identifying the clinical research needed to answer key best-practice questions.
Education
- Support and provide phage therapy education for medical, scientific, and general audiences.
- Help develop the medical and pharmaceutical infrastructure needed for the practical application of phage therapy.
Conditions We Are Currently Focused On
Diabetic Foot Infections
We are focused on infections of the bone, or osteomyelitis, that occur after antibiotics and appropriate surgical care have failed. For many of these patients, the standard treatment is amputation. However, we and others have shown that these infections can be treated with phage therapy, significantly reducing the need for amputation.
C. difficile Infection and Antibiotic Resistance
Phages are closely connected to the problem of antibiotic resistance and the dysbiosis that can lead to infection with C. difficile and other multidrug-resistant organisms. For patients treated for recurrent C. difficile infections, one related therapeutic approach is fecal microbiota transplant, or FMT.